Multiple Myeloma

Multiple myeloma is a cancer of the bone marrow that results in production of abnormal blood plasma cells. The disease is linked to substantial morbidity and mortality, and there is currently no cure. Patients being treated for multiple myeloma will experience symptom free periods, but they will relapse as the disease develops resistance to the treatment.
Multiple myeloma is a plasma cell neoplasm associated with substantial morbidity and mortality

Multiple myeloma in numbers

Classic CRAB symptoms

Disease Course - Multiple Myeloma is characterized by a pattern of remission and relapse following conventional chemotherapy

Relapsed and Refractory Multiple Myeloma

Extramedullary Disease (EMD) - Presence of extra-skeletal (ie, soft tissue or visceral) clonal plasma cell infiltrates

Patients vith soft tissue-related EMD had poorer prognosis than those with bone-related EMD

The incurable nature of multiple myeloma necessitates the development of novel agents