Oncopeptides is a science and data driven company. We are innovative and curious, and committed to bringing innovation to patients with rare hematological diseases. We are passionate to make a difference for patients who have an urgent need for better treatment options.

 

Melflufen

Melflufen (INN melphalan flufenamide) is an investigational first in class peptide-drug conjugate that targets aminopeptidases and releases alkylating agents into tumor cells.

Mechanism of Action

Melflufen is rapidly taken up by myeloma cells due to its high lipophilicity and is immediately hydrolyzed by peptidases to release an entrapped hydrophilic alkylator payload.